Syllabus(Veterinary Environmental Sciences)

Doctoral Program

No. Title Instructor Credit Semester Notes
Special Method and Practice in Advanced Veterinary Science All faculty members 1 Oct-Mar Compulsory
Special Seminar: Veterinary Environmantal Sciences A All faculty members 2 Apr-Sep Compulsory
Special Seminar: Veterinary Environmantal Sciences B All faculty members 2 Oct-Mar Compulsory
Special Seminar: Veterinary Environmantal Sciences C All faculty members 2 Apr-Sep Compulsory
Special Study: Veterinary Environmantal Sciences A All faculty members 2 Apr-Sep Compulsory
Special Study: Veterinary Environmantal Sciences B All faculty members 2 Oct-Mar Compulsory
Special Study: Veterinary Environmantal Sciences C All faculty members 2 Apr-Sep Compulsory
Special Study: Veterinary Environmantal Sciences D All faculty members 2 Oct-Mar Compulsory
Special Study: Veterinary Environmantal Sciences E All faculty members 2 Apr-Sep Compulsory
Special Study: Veterinary Environmantal Sciences F All faculty members 2 Oct-Mar Compulsory
Special Study: Veterinary Environmantal Sciences G All faculty members 2 Apr-Sep Compulsory
Special Study: Veterinary Environmantal Sciences H All faculty members 2 Oct-Mar Compulsory
Special Lecture: Bioenvironmental Sciences A Kazuhiko NISHIMURA 1 Apr-Sep
Special Lecture: Bioenvironmental Sciences B Masami MIYAKE,
Takeshi MATSUZAWA
1 Oct-Mar
Special Lecture: Bioenvironmental Sciences C Shinobu WATARAI 1 Oct-Mar
Special Lecture: Infectious Diseases Control A Yoshiyuki SETO,
Tomoko TAJIMA
1 Apr-Sep
Special Lecture: Infectious Diseases Control B Masafumi MUKAMOTO 1 Apr-Sep
Special Lecture: Infectious Diseases Control C Shinji YAMASAKI,
Makoto MATSUBAYASHI
1 Oct-Mar
Special Practice for up-to-date Instrument Application All faculty members 1 Oct-Mar
Special Lecture for Animal Ethics Toshiya OKADA 1 Apr-Sep
Internship for Advanced Veterinary Sciences All faculty members 1 Year-round
Special Lecture: Veterinary Environmental Sciences TBD 1 Apr-Sep intensive course
Special Lecture: Animal Biotechnology TBD 1 Apr-Sep intensive course

Notes

1. You must obtain at least a total of 31 credits, comprised of 24 credits for compulsory subjects, including ‘Research Integrity B’ of the Graduate School Common Courses, and 7 credits for elective subjects.

2. Of the 7 credits for elective subjects, 4 credits may be from other fields in the Division of Veterinary Science.

3. Among the elective courses from other fields, ‘Technology-based-Entrepreneurship Course II’ (1 credit) from the Graduate School Common Courses may also be included.

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Doctoral Program

Title Special Methods and Practice in Advanced Veterinary Science
Instructors Faculty of the Department of Veterinary Environmental Sciences
Course Objectives The goal of this course is to obtain basic knowledge and technology for the latest investigative approaches in order to acquire the abilities for developing an advanced research originally, and for accomplishing research independently.
Description and program The research seminar, which is usually held in each laboratory, will be held by the department or division. Research development will be improved by question-and-answer sessions, and by discussion with the researchers in different laboratories.

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Title Special Seminar: Veterinary Environmental Sciences A
Instructors Faculty of the Department of Veterinary Environmental Sciences
Course Objectives The goal of this course is to acquire advanced expertise in veterinary science and the related area, especially in the Department of Veterinary Environmental Sciences being composed of Toxicology, Veterinary Public Health, Veterinary Immunology, Veterinary Microbiology, Veterinary Epidemiology, and International Prevention of Epidemics.
Description and program Advanced expertise in Veterinary Environmental Sciences or related areas is acquired. Bibliographical survey of recent research trends through discussion with the academic supervisor will be summarized and a presentation made in order to develop problem analysis and proposal abilities for research in these areas.

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Title Special Seminar: Veterinary Environmental Sciences B
Instructors Faculty of the Department of Veterinary Environmental Sciences
Course Objectives The goal of this course is to acquire advanced expertise in veterinary science and the related area, especially in the Department Veterinary Environmental Sciences being composed of Toxicology, Veterinary Public Health, Veterinary Immunology, Veterinary Microbiology, Veterinary Epidemiology, and International Prevention of Epidemics.
Description and program A presentation of a research article review will be made at an assembly of the Division of Veterinary Science on a specific topic in Veterinary Sciences or Veterinary Environmental Sciences. In the review presentation, extensive recent knowledge from many research articles should be summarized and organized with additional personal opinions. The abstract of the review presentation should be distributed in advance to all faculties and postgraduate students in the Division of Veterinary Science in order to facilitate better discussion. Participation in the discussion is mandatory.

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Title Special Seminar: Veterinary Environmental Sciences C
Instructors Faculty of the Department of Veterinary Environmental Sciences
Course Objectives The goal of this course is to acquire advanced expertise in veterinary science and the related area, especially in the Department Veterinary Environmental Sciences being composed of Toxicology, Veterinary Public Health, Veterinary Immunology, Veterinary Microbiology, Veterinary Epidemiology, and International Prevention of Epidemics.
Description and program The ability to evaluate and analyze as a researcher and/or educator is cultivated by extensive reading of research articles related to the doctoral thesis. In addition, information on research and careers after graduate school is acquired by understanding the latest research directions in biological areas through discussions with academic supervisors.

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Title Special Study: Veterinary Environmental Sciences A
Instructors Faculty of the Department of Veterinary Environmental Sciences
Course Objectives The goal of this course is to acquire specialized skills and problem-solving abilities necessary to plan, execute, evaluate, and summarize the research in the Department of Veterinary Environmental Sciences being composed of Toxicology”, Veterinary Public Health, Veterinary Immunology, Veterinary Microbiology, Veterinary Epidemiology, and International Prevention of Epidemics.
Description and program Under the supervision of academic supervisors in the major subject, understanding and analyzing information on recent research directions will develop the ability to focus on personal topics, including original research proposals. Problem analysis and proposal abilities are developed.

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Title Special Study: Veterinary Environmental Sciences B
Instructors Faculty of the Department of Veterinary Environmental Sciences
Course Objectives The goal of this course is to acquire specialized skills and problem-solving abilities necessary to plan, execute, evaluate, and summarize the research in the Department of Veterinary Environmental Sciences being composed of Toxicology, Veterinary Public Health, Veterinary Immunology, Veterinary Microbiology, Veterinary Epidemiology, and International Prevention of Epidemics.
Description and program The goal of this course is to acquire specialized skills and problem-solving abilities necessary to plan, execute, evaluate, and summarize the research in the Department of Veterinary Environmental Sciences being composed of Toxicology, Veterinary Public Health, Veterinary Immunology, Veterinary Microbiology, Veterinary Epidemiology, and International Prevention of Epidemics.

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Title Special Study: Veterinary Environmental Sciences C
Instructors Faculty of the Department of Veterinary Environmental Sciences
Course Objectives The goal of this course is to acquire specialized skills and problem-solving abilities necessary to plan, execute, evaluate, and summarize the research in the Department Veterinary Environmental Sciences being composed of Toxicology, Veterinary Public Health, Veterinary Immunology, Veterinary Microbiology, Veterinary Epidemiology, and International Prevention of Epidemics.
Description and program Research plans will be improved through discussion with the members of the faculty other than the supervisor. New ideas for research methods, systematic recognition, assessment capability, and communications skills will be acquired.

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Title Special Study: Veterinary Environmental Sciences D
Instructors Faculty of the Department of Veterinary Environmental Sciences
Course Objectives The goal of this course is to acquire specialized skills and problem-solving abilities necessary to plan, to execute, to evaluate, and to summarize research in the Department of Veterinary Environmental Sciences being composed of Toxicology, Veterinary Public Health, Veterinary Immunology, Veterinary Microbiology, Veterinary Epidemiology, and International Prevention of Epidemics.
Description and program A series of independent experiments and survey results are logically combined, discussed with the academic supervisor of the graduate school, presented at a research report association and related relevant societies, and the findings and problems with the study results are discussed. Logical thinking, presentation skills, and proceedings management ability are acquired.

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Title Special Study: Veterinary Environmental Sciences E
Instructors Faculty of the Department of Veterinary Environmental Sciences
Course Objectives The goal of this course is to acquire specialized skills and problem-solving abilities necessary to plan, execute, evaluate, and summarize research in the department of Veterinary Environmental Sciences being composed of Toxicology, Veterinary Public Health, Veterinary Immunology, Veterinary Microbiology, Veterinary Epidemiology, and International Prevention of Epidemics.
Description and program Specialized skills and problem-solving ability necessary to summarize the research and investigation are acquired for a research topic with advice from the academic supervisor of the graduate school. Independent research and investigation, reexamination of the problem, and the achievement level are confirmed, and future development is discussed with the graduate school academic supervisor.

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Title Special Study: Veterinary Environmental Sciences F
Instructors Faculty of the Department of Veterinary Environmental Sciences
Course Objectives The goal of this course is to acquire specialized skills and problem-solving abilities necessary to plan, execute, evaluate, and summarize research in the department of Veterinary Environmental Sciences being composed of Toxicology, Veterinary Public Health, Veterinary Immunology, Veterinary Microbiology, Veterinary Epidemiology, and International Prevention of Epidemics.
Description and program Midterm presentation: progress report on the recent research direction of the degree thesis and a series of the study results should be made to discuss with the faculty and students in the division. The abstract of the presentation should be distributed in advance to all faculty and postgraduate students in the Division of Veterinary Science in order to facilitate better discussion. Participation in the discussion is mandatory.

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Title Special Study: Veterinary Environmental Sciences G
Instructors Faculty of the Department of Veterinary Environmental Sciences
Course Objectives The goal of this course is to acquire specialized skills and problem-solving abilities necessary to plan, execute, evaluate, and summarize research in the department of Veterinary Environmental Sciences being composed of Toxicology, Veterinary Public Health, Veterinary Immunology, Veterinary Microbiology, Veterinary Epidemiology, and International Prevention of Epidemics.
Description and program Consideration of the research topic based on the obtained study results by investigating related literature, aiming at the content and submission to a scientific journal with review by the referees. The ability to publish research is acquired by writing a manuscript according to the contribution regulations and the comments by the referees is developed.

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Title Special Study: Veterinary Environmental Sciences H
Instructors Faculty of the Department of Veterinary Environmental Sciences
Course Objectives The goal of this course is to acquire specialized skills and problem-solving abilities necessary to plan, execute, evaluate, and summarize research in the department of Veterinary Environmental Sciences being composed of Toxicology, Veterinary Public Health, Veterinary Immunology, Veterinary Microbiology, Veterinary Epidemiology, and International Prevention of Epidemics.
Description and program Research topics in the major subject are discussed with the academic supervisor of the graduate school, and the series of experimentations and investigation is combined with reference to the latest information in a field of research to bring the doctoral thesis to completion.

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Title Special Lecture: Bioenvironmental Sciences A
Instructors Kazuhiko NISHIMURA (Toxicology)
Course Objectives Bioenvironmental Science A concerns modern toxicology, which extends beyond the study of the toxic effects of exogenous agents by assimilating knowledge and techniques from many branches of biochemistry, biology, genetics pharmacology, and physiology, and applies safety evaluation and risk assessment to the discipline. Living organisms are exposed to various chemicals which cause toxic effects. Students learn the nature of these effects (including their cellular, biochemical, and molecular mechanisms of action) and protection mechanisms in the cells and whole body from the toxic effects.
Description and program This lecture deals recent topics on the following themes.
1. Mechanism of anemia. Relationship among hematopoiesis, regulating factors, and chemicals. Evaluation methods of toxicity to hematopoiesis.
2. Regulation of erythropoietin production has an important role in hematopoiesis.
3. Cell protective effect of erythropoietin as a non-hematopoietic effect.
4. Regulation with a variety of cell protective action, including erythropoietin.

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Title Special Lecture: Bioenvironmental Sciences B
Instructors Masami MIYAKE, Takeshi MATSUZAWA (Veterinary Public Health)
Course Objectives Food safety assurance is a prerequisite to maintain healthy human life, however, risk factors that often threaten health can occur and cause problematic food poisoning. In this course, we focus on the mechanisms, on a molecular basis, of how such risk factors cause food poisoning. The latest information on the cellular physiology of pathogenic bacteria will help to elucidate the theory that governs risk management, and increase the ability to solve issues concerning zoonoses, environmental hygiene, and food hygiene.
Description and program In this course, we cover the host-parasite relationship in depth to the molecular level, focusing on the interface between the processes of food production and circulation, and the life cycle of pathogenic bacteria. The lectures will be interactive, valuing communucation between students and the lecturer. Such interaction will reveal the underlying issues in more detail and provide current information. The course includes opportunities for free discussion and presentation, focusing on the subjects below:
1. The bacterial life cycle and cross-contamination with food
2. The plasticity of the physiology of pathogenic bacteria
3. What are the differences between host and non-host environments?
4. Cross-talk between environmental responses
5. Controlling bacterial virulence by disrupting the environmental response process
6. Free discussion and presentation

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Title Special Lecture: Bioenvironmental Sciences C
Instructors Shinobu WATARAI (Veterinary Immunology)
Course Objectives Immune responses are highly organized physiological mechanisms that are fundamental for the maintenance of animal life. Immune reactions proceed under regulation cell-to-cell interactions among immunocompetent cells. Cytokine productions, as well as interactions between the immune system and nervous and endocrine systems also participate. The immune system responds to abnormal conditions, such as stress and tumors, and invading antigens, such as infectious organisms or allergens. This course aims to provide information on the role of immunocompetent cells and cytokines that regulate immune responses and the maintenance of homeostasis. This course also introduces the protective immunity of animals, and pathogenic conditions caused by immunological disorders.
Description and program We introduce the molecular immune mechanisms characteristic of mammals, birds and lower vertebrates such as fish. These include 1. phylogeny and ontogeny of immune systems, 2-4. differentiation of immunocompetent cells, cell surface receptors that affect immunological functions, tissue- or cell-derived humoral factors such as cytokines and complements, and role of immunoglobulins, 5-6. specific and non-specific protective immune mechanisms against infections, and 7-8. transplantation immunity, anti-tumor immunity, immune disorders and allergies.

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Title Special Lecture: Infectious Disease Control A
Instructors Yoshiyuki SETO, Tomoko TAJIMA (Veterinary Microbiology)
Course Objectives To understand the pathogenic microorganisms responsible for infectious diseases in livestock and poultry in terms of the host-parasite relationship, this lecture focuses on the pathogenic and immunological properties of microbial pathogens responsible for animal infectious diseases. To understand the protection mechanism against infectious diseases, both innate and acquired immunity will also be addressed.
Description and program To gain advanced knowledge on animal infectious diseases, including emerging and re-emerging infectious diseases, newly published findings will be discussed. To nurture high-level communication and presentation skills, published articles describing the topics listed below will be selected and used for presentation.
1. Bacterial infection (3)
2. Viral infection (3)
3. Emerging and re-emerging infectious diseases (1)
4. Protection against infectious diseases (1)

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Title Special Lecture: Infectious Disease Control B
Instructors Masafumi MUKAMOTO (Veterinary Epideminology)
Course Objectives In the area of veterinary medicine, infectioous disease control based on mass prophylaxis is a very important problem. The aims of this lecture are to deepen knowledge of the analysis of pathogenic factors, host and environmental factors in relation to the realization of disease control and planning of prophylaxis countermeasures.
Description and program The latest research on the following items and understanding of infectious disease control is increased.
1: Mechanisms of expressions of colonization factors, entry factors, anti-phagocytic factors and toxins as virulent factors from pathogenic microbes and host responses to them. (3)
2: Defense mechanisms against infections in relation to sensitive hosts and mode of transmission.
3: Latest findings on the interrelationship between pathogens and hosts.

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Title Special Lecture: Infectious Disease Control C
Instructors Shinji YAMASAKI, Makoto MATSUBAYASHI (International Prevention of Epidemics)
Course Objectives The issue of infectious diseases was thought to be solved. However, the emerging and re-emerging infectious diseases have been increasingly becoming a global threat. Because of the rapid globalization, mass transportation of people as well as agricultural and industrial products beyond the border may result in spreading various pathogens even in areas where such pathogens were not present. Teaching from a global point of view about the characterization of emerging and re-emerging pathogens and the diseases they cause by discussing the latest epidemiologic as well as scientific data, capability to solve and control the issues of emerging and re-emerging infectious diseases will be brought into the limelight.
Description and program We introduce the following subjects by using the latest research and review articles and discuss the utility of the molecular typing methods. Therefore, PhD students are expected to acquire the accurate and advanced knowledge in the following subjects and the capability for understanding the research articles in depth.
1.Basic knowledge and theory about molecular epidemiology
2-4. Applications of molecular typing methods
5. Issues of antimicrobial resistance
6. Important bacteria causing food poisoning globally
7. Important bacteria causing food-poisoning in domestic

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Title Special Practice for up-to-date Instrument Application
Instructors Faculty in the Division of Veterinary Science
Course Objectives The goal of this course is to obtain the principles and limitations of the latest technologies in bioscience in order to carry out independent quality research.
Description and program Learning the principles and limitations of the latest technologies in bioscience is indispensable for the development of independent research. It should be recognized what is possible using novel scientific equipment. Concrete experience of the apparatus may enable its application in independent research.

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Title Special Lecture on Animal Ethics
Instructors Toshiya OKADA (Laboratory Animal Science)
Course Objectives In this lecture, we will investigate the laws and regulations concerning animal welfare and the ethical discipline necessary for scientists using live animals.
Description and program The laws and regulations discussed in this lecture include the following: Law for the Humane Treatment and Management of Animals and its related legal information (Standards Relating to the Care and Management of Laboratory Animals and Relief of Pain; Guidelines on Methods of Sacrificing Laboratory Animals; Standards Relating to the Care and Management of Pets, Sandards Relating to the Care and Management of Domestic Animals; Standards Relating to the Care and Management of Animals for Exhibition; and Invasive Alien Species Law), Law Concerning the Conservation and Sustainable Use of Biological Diversity through Regulations on the Use of Living Modified Organisms and Law concerning Prevention of Infectious Diseases and Medical Care for Patients with Infectious Diseases. We will also examine the welfare of various animals, including domestic animals, companion animals, animals for exhibition and laboratory animals, and discuss ethical issues surrounding the relationship between humans and animals.

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Title Internship for Advanced Veterinary Science
Instructors Faculty of the Division of Veterinary Science
Course Objectives The goal of this course is to experience occupational positions in order to increase the possibility of obtaining a position as a researcher or professional scientific investigator.
Description and program